Wednesday, May 9, 2012

bone marrow and cell grow factors by Zeng at University of Florida

a new combination therapy that reverses established Type 1 diabetes in mice. ... The two-step regimen involves bone marrow transplantation and substances that promote the growth of cells that produce insulin, the sugar-regulating hormone that is missing in people who have Type 1 diabetes.

News article:

Monday, May 7, 2012

Hyperbaric Oxygen by Pileggi at Diabetes Research Institute

Hyperbaric Oxygen treatment is basically putting people in a chamber with extra oxygen at higher pressure. In these experiments, animals were put in 100% oxygen at twice normal atmospheric pressure.

Quotes from the abstract:
Spontaneous diabetes incidence reduced from 85% in controls to 65% in  [hyperbaric oxygen treatment]  (P = 0.01). ... Cyclophosphamide-induced diabetes onset was reduced from 85.3% in controls to 48% after [hyperbaric oxygen treatment] (P < 0.005) and paralleled by lower insulitis. 
Quote from the news article:
In mice, the treatment caused changes in the immune system's response to newly developing diabetes, and reduced the risk of diabetes between 20 and 40 percent. In the mice that still developed diabetes, the hyperbaric therapy delayed disease progression, the investigators found.

News article: